- Membrane Builder 1.0
- A tool to construct membrane bilayer
Challenge for the construction of the initial lipid bilayer is the main problem in setting up a simulation for membrane proteins considering protein dynamics, folding, and the mechanism of action. Almost all membrane models used in molecular dynamics simula- tions are usually composed of only one type of phospholipids mole- cule that is quite far from the native biological state, because biolog- ical membranes contain various types of lipids. Moreover, the asymmetry of lipid composition of the lipid bilayer is functionally important. In this regard, we provide the MemBuilder server to pre- pare the initial configuration of a membrane model composed of different phospholipid molecules. This server is also dedicated to determine the lipid composition of each monolayer to support the asymmetry of the membrane bilayer.