Replacement of protein segments with external peptide fragments is an efficient method.
in the design of novel engineered protein, a researcher confronts with selection of appropriate peptide fragments.
These peptides are used to alter protein properties and mimic protein structures in a manner that the overall fold of
protein largely preserve. The peptide fragment proposer (PFpro) web server is a new service to propose a set of appropriate
peptide using the structural and physicochemical characteristics of user's input pdb file. The output page provides a list of
distinct fragments found by a search for best candidates in more than 600 million peptides.