MemBuilder is a web-based
graphical user interface to generate homogenous and heterogenous lipid
bilayers. It is implemented by using Perl and C programming languages
and Java Script is also partly appplied to make web interface.
Users on MemBuilder can specify type and concentration of lipid
molecules to build desired membrane. MemBuilder has eighteen different
lipid molecules and support four different force fields including both
all-atom and united-atom force fields that can be selected upon users' request.
MemBuilder randomly place selected lipids to build the whole membrane and then performs energy minimization
at the presence of water and ions to decrease local stresses inside the
lipid bilayer that will take a few minutes according to the system size.
This web server help the user to generate GROMACS input files necessary
to build a membrane system for molecular dynamics simulation.
Please note that
Download GROMOS43a1-S3 and Slipid/AMBER force field sources from
download page and put them into the GROMACS directory = /usr/local/gromacs/share/top.
Download topology file (.itp) for each selected lipid molecule and put
it in the work directory that you want to run simulation.